Dihydrofolate Reductase Antikörper (AbBy Fluor® 350)
Kurzübersicht für Dihydrofolate Reductase Antikörper (AbBy Fluor® 350) (ABIN1400589)
Target
Alle Dihydrofolate Reductase (DHFR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- DHFR Polyclonal Antibody, AbBy Fluor-350 Conjugated
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DHFR
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Isotyp
- IgG
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anti-Dihydrofolate Reductase (DHFR) (AA 88-187) antibody
DHFR Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2B10 unconjugated
anti-Dihydrofolate Reductase (DHFR) antibodyDHFR Reaktivität: Human, Hund, Affe WB, IHC, IF, IHC (p) Wirt: Maus Monoclonal 6G7 unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 2-187) antibodyDHFR Reaktivität: Human, Maus, Ratte WB, IHC, IF, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Dihydrofolate Reductase (DHFR) antibodyDHFR Reaktivität: Human WB, IHC, ELISA, IP Wirt: Kaninchen Monoclonal 9B2 unconjugated Recombinant Antibody
anti-Dihydrofolate Reductase (DHFR) antibodyKD Validated DHFR Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB3575 unconjugated Recombinant Antibody
anti-Dihydrofolate Reductase (DHFR) (AA 1-50) antibodyDHFR Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 135-164) antibodyDHFR Reaktivität: Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 16-30), (N-Term) antibodyDHFR Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB49346 unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 1-187) antibodyDHFR Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Dihydrofolate Reductase (DHFR) (AA 1-186) antibodyDHFR Reaktivität: Human, Maus, Ratte, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 49-DHFR unconjugated
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Applikationshinweise
- IF(1:50-200)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Dihydrofolate Reductase (DHFR)
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Andere Bezeichnung
- DHFR
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Hintergrund
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Synonyms: DHFR, DHFRP1, Dihydrofolate reductase, DYR, DYR_HUMAN, EC 1.5.1.3.
Background: DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive.
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Molekulargewicht
- 21kDa
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Gen-ID
- 1719
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HGNC
- 0
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UniProt
- P00374
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Pathways
- Mitotic G1-G1/S Phases
Target
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