Dihydrofolate Reductase Antikörper

Produktnummer ABIN7253152

Produktdetails anti-Dihydrofolate Reductase Antikörper

Target: Dihydrofolate Reductase (DHFR)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dihydrofolate Reductase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of human DHFR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dihydrofolate Reductase

Target: Dihydrofolate Reductase (DHFR)

Andere Bezeichnung: DHFR (DHFR Produkte)

Synonyme: DHFR antikoerper, F10_orf160 antikoerper, ECK0049 antikoerper, JW0047 antikoerper, tmrA antikoerper, cb595 antikoerper, zgc:86637 antikoerper, DDBDRAFT_0187132 antikoerper, DDBDRAFT_0230113 antikoerper, DDB_0187132 antikoerper, DDB_0230113 antikoerper, CG14887 antikoerper, Dmel\\CG14887 antikoerper, dhfr antikoerper, DHFRP1 antikoerper, DYR antikoerper, 8430436I03Rik antikoerper, AA607882 antikoerper, AI662710 antikoerper, AW555094 antikoerper, Dhfr1 antikoerper, confers resistance to sulfonamides antikoerper, dihydrofolate reductase antikoerper, dihydrofolate reductase DhfR antikoerper, Dihydrofolate reductase antikoerper, dhfr antikoerper, DHFR antikoerper, dhfR antikoerper, folA antikoerper, dfrA antikoerper, LOC707382 antikoerper, CNJ01940 antikoerper, DDB_G0286755 antikoerper, Dhfr antikoerper, Mesil_0096 antikoerper, Arch_0408 antikoerper, Fbal_3367 antikoerper, Ilyop_0482 antikoerper, Lbys_2007 antikoerper, Riean_0733 antikoerper, Mrub_1855 antikoerper, Poras_0766 antikoerper, Halhy_3552 antikoerper, Mesop_3614 antikoerper, LOC609048 antikoerper

Hintergrund: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 21 kDa

UniProt: P00374

Pathways: Mitotic G1-G1/S Phases