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DIS3L2 Antikörper (AbBy Fluor® 488)

This anti-DIS3L2 antibody (ABIN1400560) is a Rabbit Polyclonal antibody detecting DIS3L2 in WB, IF (p). Suitable for Human, Mouse, Rat.
Produktnummer ABIN1400560

Kurzübersicht für DIS3L2 Antikörper (AbBy Fluor® 488) (ABIN1400560)

Target

Alle DIS3L2 Antikörper anzeigen
DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

Reaktivität

  • 36
  • 19
  • 19
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 27
  • 9
  • 1
Kaninchen

Klonalität

  • 29
  • 8
Polyklonal

Konjugat

  • 13
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DIS3L2 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation

  • 25
  • 12
  • 7
  • 6
  • 6
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DIS3L2

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))

    Andere Bezeichnung

    DIS3L2

    Hintergrund

    Synonyms: DIS3 L2, DIS3 mitotic control homolog S. cerevisiae like 2, DIS3 mitotic control homolog like 2, FLJ36974, MGC42174, DI3L2_HUMAN.

    Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3? region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3? processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events.

    Gen-ID

    129563

    Pathways

    Stem Cell Maintenance
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