DIS3L2 Antikörper (AbBy Fluor® 488)
Kurzübersicht für DIS3L2 Antikörper (AbBy Fluor® 488) (ABIN1400560)
Target
Alle DIS3L2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Kreuzreaktivität
- Human, Maus, Ratte
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                                            Aufreinigung
- Purified by Protein A.
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                                            Immunogen
- KLH conjugated synthetic peptide derived from human DIS3L2
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- IF(IHC-P) 1:50-200
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Konzentration
- 1 μg/μL
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                                            Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            Konservierungsmittel
- ProClin
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                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            Haltbarkeit
- 12 months
 
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    - DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
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                                            Andere Bezeichnung
- DIS3L2
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                                            Hintergrund
- 
                        Synonyms: DIS3 L2, DIS3 mitotic control homolog S. cerevisiae like 2, DIS3 mitotic control homolog like 2, FLJ36974, MGC42174, DI3L2_HUMAN. Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3? region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3? processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events. 
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                                            Gen-ID
- 129563
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                                            Pathways
- Stem Cell Maintenance
 Target
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