Transglutaminase 2 Antikörper (AA 351-450) (FITC)
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- Target Alle Transglutaminase 2 (TGM2) Antikörper anzeigen
- Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
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Bindungsspezifität
- AA 351-450
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Transglutaminase 2 Antikörper ist konjugiert mit FITC
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Transglutaminase 2
- Isotyp
- IgG
- Top Product
- Discover our top product TGM2 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
- Andere Bezeichnung
- Transglutaminase 2 (TGM2 Produkte)
- Synonyme
- G-ALPHA-h antikoerper, GNAH antikoerper, TG2 antikoerper, TGC antikoerper, tgm2 antikoerper, zgc:101081 antikoerper, TgaseII antikoerper, TGM2 antikoerper, fc12b04 antikoerper, wu:fc12b04 antikoerper, zgc:136700 antikoerper, TGL2 antikoerper, G[a]h antikoerper, TGase2 antikoerper, tTG antikoerper, tTGas antikoerper, transglutaminase 2 antikoerper, transglutaminase 2, C polypeptide A antikoerper, transglutaminase 2b antikoerper, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antikoerper, transglutaminase 2, C polypeptide antikoerper, TGM2 antikoerper, tgm2a antikoerper, Tgm2 antikoerper, tgm2b antikoerper
- Hintergrund
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Synonyms: TG 2, TGC, TG2, TGase C, TGase H, TGase-2, TGase2, TgaseII, ALPHA SUBUNIT, C polypeptide, G alpha h, G protein alpha subunit Gh class, G[a]h, Gh CLASS G ALPHA h, GNAH, GNAH G PROTEIN, Guanine nucleotide binding protein H polypeptide, H POLYPEPTIDE, Protein glutamine gamma glutamyltransferase 2, Protein glutamine gamma glutamyltransferase, Protein-glutamine gamma-glutamyltransferase 2, TGC, TGC GUANINE NUCLEOTIDE BINDING PROTEIN, TGM 2, TGM2, TGM2_HUMAN, Tissue transglutaminase, Tissue type transglutaminase, Transglutaminase 2, Transglutaminase 2 C polypeptide, Transglutaminase C, Transglutaminase H, Transglutaminase-2, tTG, tTGas.
Background: Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and g-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes that catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes, including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. Human keratinocyte transglutaminase (TGase1) is a membrane associated, 817 amino acid protein. Human tissue transglutaminase (TGase2) is an endothelial cell specific, 687 amino acid protein.
- Pathways
- Tube Formation, Thromboxane A2 Receptor Signaling
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