TFAM Antikörper (AA 155-246) (FITC)
Kurzübersicht für TFAM Antikörper (AA 155-246) (FITC) (ABIN1399526)
Target
Alle TFAM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 155-246
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Kreuzreaktivität
- Maus, Ratte
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Homologie
- Human,Dog,Cow,Sheep,Pig,Rabbit,Goat
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human MtTF1
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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Andere Bezeichnung
- MtTF1
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Hintergrund
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Synonyms: TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, TCF-6, Transcription factor 6-like 2, TFAM
Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
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Gen-ID
- 7019
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UniProt
- Q00059
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Pathways
- Chromatin Binding
Target
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