FBXO15 Antikörper (AA 101-200) (AbBy Fluor® 555)

Produktnummer ABIN1398845

Der Kaninchen Polyklonal Anti-FBXO15 Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, FBXO15 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für FBXO15 Antikörper (AA 101-200) (AbBy Fluor® 555) (ABIN1398845)

Target: FBXO15 (F-Box Protein 15 (FBXO15))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO15 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-FBXO15 Antikörper (AbBy Fluor® 555)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Fbx15

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FBXO15

Target: FBXO15 (F-Box Protein 15 (FBXO15))

Andere Bezeichnung: Fbx15

Hintergrund:

Synonyms: F box protein 15, F-box only protein 15, F-box protein 15, Fbxo15, MGC39671, FBX15_HUMAN.

Background: FBXO15, also known as FBX15, is a 434 amino acid protein that contains one C-terminal F-box domain and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO15 can directly interact with Skp1 p19 and CUL-1. In addition, FBXO15 is a target of the transcription factor Oct-3/4, however, it does not appear to be essential for early development and fertility.

Gen-ID: 201456