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SGK1 Antikörper (Biotin)

Dieses Anti-SGK1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SGK1 in WB und IHC (p). Geeignet für Human, Maus, Ratte, Rind (Kuh) und Hund.
Produktnummer ABIN1396980

Kurzübersicht für SGK1 Antikörper (Biotin) (ABIN1396980)

Target

Alle SGK1 Antikörper anzeigen
SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reaktivität

  • 159
  • 99
  • 81
  • 19
  • 16
  • 8
  • 7
  • 5
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Hund

Wirt

  • 144
  • 12
  • 4
  • 1
Kaninchen

Klonalität

  • 148
  • 13
Polyklonal

Konjugat

  • 69
  • 8
  • 7
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
Dieser SGK1 Antikörper ist konjugiert mit Biotin

Applikation

  • 129
  • 52
  • 50
  • 46
  • 40
  • 35
  • 27
  • 24
  • 9
  • 9
  • 7
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Rind (Kuh), Hund, Human, Maus, Ratte

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human SGK1

    Isotyp

    IgG
  • Applikationshinweise

    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

    Andere Bezeichnung

    SGK1

    Hintergrund

    Synonyms: Serum/glucocorticoid regulated kinase 1, SGK 1, SGK-1, Serine/threonine protein kinase SGK, Serine/threonine protein kinase Sgk1, Serum and glucocorticoid regulated kinase, Serum/glucocorticoid regulated kinase, SGK 1, SGK.

    Background: SGK1 is a protein kinase that plays an important role in cellular stress response. SGK1 activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels of SGK1 and activity may contribute to conditions such as hypertension and diabetic nephropathy. This protein also mediates cell survival signals, as it has been shown to phosphorylate and negatively regulate the pro apoptotic FOXO3A protein. Ser 422 is a critical site on the protein and may be involved in its activation.

    Molekulargewicht

    49kDa

    Pathways

    MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway
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