NMUR2 Antikörper (AA 181-230)

Produktnummer ABIN1387943

Produktdetails anti-NMUR2 Antikörper

Target: NMUR2 (Neuromedin U Receptor 2 (NMUR2))

Bindungsspezifität: AA 181-230

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMUR2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NMUR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NMUR2

Target: NMUR2 (Neuromedin U Receptor 2 (NMUR2))

Andere Bezeichnung: NMUR2/GPR-FM4 (NMUR2 Produkte)

Synonyme: NMUR2 antikoerper, NMSR2 antikoerper, FM-4 antikoerper, FM4 antikoerper, NMU-R2 antikoerper, NMU2R antikoerper, TGR-1 antikoerper, TGR1 antikoerper, Nmu2r antikoerper, neuromedin U receptor 2 antikoerper, NMUR2 antikoerper, Nmur2 antikoerper

Hintergrund:

Synonyms: FM4, G protein coupled receptor FM 4, G protein coupled receptor TGR 1, G-protein coupled receptor FM-4, G-protein coupled receptor TGR-1, Neuromedin U receptor 2, Neuromedin-U receptor 2, NMU R2, NMU-R2, NMU2R, NMUR2, NMUR2_HUMAN, TGR1

Background: Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. It?s expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.

Gen-ID: 56923

UniProt: Q9GZQ4

Pathways: Feeding Behaviour