PVRL4 Antikörper (AA 151-250)

Produktnummer ABIN1387848

Dieses Anti-PVRL4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PVRL4 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für PVRL4 Antikörper (AA 151-250) (ABIN1387848)

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PVRL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PVRL4 Antikörper

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nectin 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Andere Bezeichnung: Nectin 4

Hintergrund:

Synonyms: Ig superfamily receptor LNIR, Nectin 4, poliovirus receptor-related 4, PRR4, poliovirus receptor related 4.

Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Gen-ID: 59341

Pathways: Cell-Cell Junction Organization