BCL11A Antikörper (AA 751-835)

Produktnummer ABIN1387845

Dieser Anti-BCL11A Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von BCL11A in WB, ELISA, ICC, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Maus.

Kurzübersicht für BCL11A Antikörper (AA 751-835) (ABIN1387845)

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-BCL11A Antikörper

Bindungsspezifität: AA 751-835

Kreuzreaktivität: Maus

Homologie: Human,Rat,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Ctip1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BCL11A

Target: BCL11A (B-Cell CLL/lymphoma 11A (Zinc Finger Protein) (BCL11A))

Andere Bezeichnung: Ctip1/BCL-11A

Hintergrund:

Synonyms: B cell CLL/lymphoma 11A zinc finger protein, B cell CLL/lymphoma 11A zinc finger protein isoform 2, B cell CLL/lymphoma 11A, B cell lymphoma/leukaemia 11A, B-cell CLL/lymphoma 11A, B-cell lymphoma/leukemia 11A, BC11A_HUMAN, BCL 11A, BCL-11A, BCL11A, BCL11A B cell CLL/lymphoma 11A zinc finger protein isoform 1, BCL11A L, BCL11A S, BCL11A XL, BCL11AL, BCL11AS, BCL11AXL, C2H2 type zinc finger protein, COUP TF interacting protein 1, COUP-TF-interacting protein 1, Ctip 1, CTIP1, Ecotropic viral integration site 9, Ecotropic viral integration site 9 homolog, Ecotropic viral integration site 9 protein, Ecotropic viral integration site 9 protein homolog, Evi 9, EVI-9, Evi9, FLJ10173, FLJ34997, HBFQTL5, KIAA1809, Zinc finger protein 856, ZNF856.

Background: Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

Pathways: Regulation of Cell Size