RCAN1 Antikörper (AA 101-200)

Produktnummer ABIN1387813

Produktdetails anti-RCAN1 Antikörper

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCAN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calcipressin 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Andere Bezeichnung: Calcipressin 1/DSCR 1 (RCAN1 Produkte)

Synonyme: ADAPT78 antikoerper, CSP1 antikoerper, DSC1 antikoerper, DSCR1 antikoerper, MCIP1 antikoerper, RCN1 antikoerper, RCAN1 antikoerper, 2410048A02Rik antikoerper, AA408855 antikoerper, AI429645 antikoerper, AL024459 antikoerper, AV028423 antikoerper, Adapt78 antikoerper, CALP1L antikoerper, Dscr1 antikoerper, Mcip1 antikoerper, dscr1 antikoerper, rcan1 antikoerper, wu:fr92c05 antikoerper, adapt78 antikoerper, csp1 antikoerper, dsc1 antikoerper, mcip1 antikoerper, MGC53636 antikoerper, rcn1 antikoerper, MGC69428 antikoerper, regulator of calcineurin 1 antikoerper, regulator of calcineurin 1b antikoerper, regulator of calcineurin 1 L homeolog antikoerper, Down syndrome critical region gene 1 antikoerper, RCAN1 antikoerper, Rcan1 antikoerper, rcan1b antikoerper, rcan1.L antikoerper, dscr1 antikoerper, rcan1 antikoerper

Hintergrund:

Synonyms: Adapt 78, Adapt78, Calcipressin 1, Calcipressin-1, Calcium and oxidant inducible mRNA, CSP 1, CSP1, Down syndrome candidate region 1, Down syndrome critical region gene 1, Down syndrome critical region protein 1, DSC 1, DSC1, DSCR 1, DSCR1, DSCR-1, MCIP 1, MCIP1, Modulatory calcineurin interacting protein 1, Myocyte enriched calcineurin interacting protein 1, Myocyte-enriched calcineurin-interacting protein 1, Near DSCR proline rich protein, RCAN1, RCAN1_HUMAN, RCN 1, RCN1, Regulator of calcineurin 1.

Background: DSCR1 protein influences cardiac and nervous system development (1). DSCR1 is abundant in the brain, heart, and skeletal muscle. Overexpression of DSCR1 may play a role in the pathogenesis of Down syndrome, in particular mental retardation and/or cardiac defects. DSCR1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Human DSCR1 maps to gene locus 21q22.1-q22.2.

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development