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BDNF Antikörper (AA 151-247)

Dieses Anti-BDNF-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BDNF in WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human, Ratte und Maus. Dieses Primary Antibody wurde in 6+ Publikationen zitiert.
Produktnummer ABIN1387788

Kurzübersicht für BDNF Antikörper (AA 151-247) (ABIN1387788)

Target

Alle BDNF Antikörper anzeigen
BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Reaktivität

  • 139
  • 79
  • 64
  • 22
  • 17
  • 15
  • 10
  • 9
  • 8
  • 8
  • 7
  • 6
  • 3
  • 3
  • 1
Human, Ratte, Maus

Wirt

  • 135
  • 57
  • 6
  • 3
  • 2
  • 2
Kaninchen

Klonalität

  • 137
  • 67
Polyklonal

Konjugat

  • 131
  • 19
  • 12
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BDNF Antikörper ist unkonjugiert

Applikation

  • 168
  • 102
  • 77
  • 68
  • 49
  • 24
  • 18
  • 12
  • 12
  • 12
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 15
    • 14
    • 14
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-247

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human BDNF

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Nader, Ateyya, El-Shafey, El-Sherbeeny et al.: "Sitagliptin enhances the neuroprotective effect of pregabalin against pentylenetetrazole-induced acute epileptogenesis in mice: Implication of oxidative, inflammatory, apoptotic and autophagy ..." in: Neurochemistry international, (2017) (PubMed).

    Xing, Wen, Li, Xia: "Non-viral liposome-mediated transfer of brain-derived neurotrophic factor across the blood-brain barrier." in: Neural regeneration research, Vol. 11, Issue 4, pp. 617-22, (2016) (PubMed).

    Zabłocka, Mitkiewicz, Macała, Janusz: "Neurotrophic Activity of Cultured Cell Line U87 is Up-Regulated by Proline-Rich Polypeptide Complex and Its Constituent Nonapeptide." in: Cellular and molecular neurobiology, Vol. 35, Issue 7, pp. 977-86, (2016) (PubMed).

    Zhao, Li, Wei, Savage, Zhou, Ma: "Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring." in: Neurobiology of disease, Vol. 68, pp. 145-55, (2014) (PubMed).

  • Target

    BDNF (Brain-Derived Neurotrophic Factor (BDNF))

    Andere Bezeichnung

    BDNF

    Hintergrund

    Synonyms: ANON2, BULN2, Brain-derived neurotrophic factor, BDNF, Abrineurin

    Background: During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

    Gen-ID

    627

    UniProt

    P23560

    Pathways

    RTK Signalweg, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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