Geminin Antikörper (AA 110-142)
Kurzübersicht für Geminin Antikörper (AA 110-142) (ABIN1387623)
Target
Alle Geminin (GMNN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 110-142
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human Geminin
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
-
Andere Bezeichnung
- Geminin
-
Hintergrund
-
Synonyms: Gem, Geminin, GMNN
Background: Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control.
-
Gen-ID
- 51053
-
UniProt
- O75496
-
Pathways
- EGFR Signaling Pathway, DNA Replication
Target
-