PDE7A Antikörper

Produktnummer ABIN1387580

Der Kaninchen Polyklonal anti-PDE7A Antikörper wird verwendet zum Nachweis von PDE7A in Proben von Human. Er wurde validiert für WB, IF, FACS, IHC (p) und IHC (fro).

Kurzübersicht für PDE7A Antikörper (ABIN1387580)

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PDE7A Antikörper

Verwendungszweck: PDE7A Polyclonal Antibody

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDE7A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:500-2000), IHC-P(1:100-500), IHC-F(1:100-500), IF(1:100-500), Flow-Cyt(1 μg/Test)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu PDE7A

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Andere Bezeichnung: Pde7a

Hintergrund:

Synonyms: HCP 1, HCP1, High affinity cAMP specific 3'5' cyclic phosphodiesterase 7A, High affinity cAMP-specific 3'', P2A, PDE 7, PDE 7A, PDE7, PDE71, PDE7A, PDE7A_HUMAN, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, Phosphodiesterase7A, Rolipram insensitive phosphodiesterase type 7, TM 22, TM22, 5''-cyclic phosphodiesterase 7A.

Background: Phosphodiesterases (PDE, also designated cyclic nucleotide phosphodiesterase) are important for the downregulation of the intracellular level of the second messenger cyclic adenosine monophosphate (cAMP) by hydrolyzing cAMP to 5'AMP. Phosphodiesterase type 3 isoforms, PDE3A and 3B, are expressed primarily in cardiovascular tissue and adipose tissue, respectively. PDE3A, is found in myocardium and platelets and PDE3B is found in lymphocytes. The PDE7A1 (HCP1) isozyme and the PDE7A2 proteins, alternate splice products of PDE7A, are highly expressed in skeletal muscle. PDE7B is most highly expressed in pancreas. The PDE family contains proteins that serve tissue-specific roles in regulation of lipolysis, glycogenolysis, myocardial contractility, and smooth muscle relaxation.

Gen-ID: 5150

UniProt: Q13946

Pathways: cAMP Metabolic Process