PDE7A Antikörper

Produktnummer ABIN7230562

Der Kaninchen Polyklonal anti-PDE7A Antikörper wird verwendet zum Nachweis von PDE7A in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für PDE7A Antikörper (ABIN7230562)

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PDE7A Antikörper

Verwendungszweck: Rabbit Anti-PDE7A Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PDE7A protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PDE7A protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PDE7A

Target: PDE7A (phosphodiesterase 7A (PDE7A))

Andere Bezeichnung: PDE7A

Hintergrund: High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, HCP1, TM22The protein encoded by PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE7A. PDE7A (Phosphodiesterase 7A) is a Protein Coding gene. Diseases associated with PDE7A include Chronic Lymphocytic Leukemia and Low Compliance Bladder. Among its related pathways are G alpha(s) signalling events and Ectoderm Differentiation.

Molekulargewicht: 53kD

Gen-ID: 5150

UniProt: Q13946

Pathways: cAMP Metabolic Process