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PEN2 Antikörper (AA 6-80)

Name: PEN2 Antikörper (AA 6-80)
SKU: ABIN1387540
Price: 357.7 EUR
Availability: InStock

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PEN2 in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Maus und Ratte und wurde in 1 Publikation erwähnt.

Formalin-fixed and paraffin embedded mouse lung labeled with Rabbit Anti-IL-2R gamma Polyclonal Antibody (ABIN1387540) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (PEN2 Antikörper (AA 6-80))

IHC

Formalin-fixed and paraffin-embedded rat brain labeled with Anti-PEN2 Polyclonal Antibody, Unconjugated (ABIN1387540) 1:200, overnight at 4°C, The secondary antibody was Goat Anti-Rabbit IgG, Cy3conjugated used at 1:200 dilution for 40 minutes at 37°C. (PEN2 Antikörper (AA 6-80))

2 Abbildungen

(1 reference)

Produktnummer ABIN1387540

Kurzübersicht für PEN2 Antikörper (AA 6-80) (ABIN1387540)

Target

Alle PEN2 (PSENEN) Antikörper anzeigen

PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Reaktivität

Maus, Ratte

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser PEN2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Bindungsspezifität
14

4

4

3

1

1

1

1

1

1

1
AA 6-80

Spezifität

Belongs to the PEN-2 family

Kreuzreaktivität

Maus, Ratte

Homologie

Human,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human PEN2

Isotyp

IgG
anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 39-57) antibody
PSENEN Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 1-101) antibody
PSENEN Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1C12-G5 unconjugated

anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 1-50) antibody
PSENEN Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Opossum WB Wirt: Kaninchen Polyclonal unconjugated

anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 20-69) antibody
PSENEN Reaktivität: Human, Maus, Hund, Pferd, Meerschweinchen, Kaninchen, Affe, Fledermaus, Schwein WB Wirt: Kaninchen Polyclonal unconjugated

anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibody
PSENEN Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Affe, Fledermaus, Schwein, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated

anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibody
PSENEN Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated

anti-Presenilin Enhancer 2 Homolog (PSENEN) (N-Term) antibody
PSENEN Reaktivität: Human, Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated

anti-Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) antibody
PSENEN Reaktivität: Human, Maus, Ratte WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated

anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 39-57) antibody (HRP)
PSENEN Reaktivität: Human ELISA Wirt: Kaninchen Polyclonal HRP

anti-Presenilin Enhancer 2 Homolog (PSENEN) (AA 39-57) antibody (FITC)
PSENEN Reaktivität: Human Wirt: Kaninchen Polyclonal FITC

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Chu, Peng, Long, Wang, Luo, Sharma, He: "Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice." in: Acta biochimica et biophysica Sinica, Vol. 47, Issue 4, pp. 258-66, (2015) (PubMed).
Target

PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))

Andere Bezeichnung

PEN2

Hintergrund

Synonyms: PEN2, PEN-2, MDS033, MSTP064, Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

Gen-ID

55851

UniProt

Q9NZ42

Pathways

Notch Signalweg, Neurotrophin Signalübertragung