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FAS Antikörper (AA 81-170)

Name: FAS Antikörper (AA 81-170)
SKU: ABIN1387305
Price: 384.62 EUR
Availability: InStock

FAS Reaktivität: Human, Ratte, Maus WB, FACS, ELISA Wirt: Kaninchen Polyclonal unconjugated

(Human Cell Line) SW480 lysates probed with Apo-1 Polyclonal Antibody, unconjugated at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 60 minutes at 37°C. (FAS Antikörper (AA 81-170))

1 image

(1 reference)

Produktnummer ABIN1387305

Datenblatt (PDF)

Target Alle FAS Antikörper anzeigen

FAS (TNF Receptor Superfamily, Member 6 (FAS))
Bindungsspezifität
25

16

15

8

8

6

5

5

4

4

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 81-170
Reaktivität
226

67

65

19

9

5

4

4

3

3

2

1

1

1
Human, Ratte, Maus
Wirt
158

102

4

3

2

1

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
155

116

1
Polyklonal
Konjugat
130

29

25

12

11

7

5

5

3

3

3

3

3

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser FAS Antikörper ist unkonjugiert
Applikation
166

130

74

68

40

36

34

26

26

20

19

12

8

6

5

4

4

2

2

2

2

2

2

2

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA

Kreuzreaktivität

Human, Maus, Ratte

Homologie

Pig

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human FAS/Apo-1

Isotyp

IgG

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anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibody
FAS Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 1B6 unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Fang, Zhang, Qi, Fan, Luo, Liu, Tan: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).
Target

FAS (TNF Receptor Superfamily, Member 6 (FAS))

Andere Bezeichnung

Apo-1 (FAS Produkte)

Synonyme

ALPS1A antikoerper, APO-1 antikoerper, APT1 antikoerper, CD95 antikoerper, FAS1 antikoerper, FASTM antikoerper, TNFRSF6 antikoerper, AI196731 antikoerper, APO1 antikoerper, TNFR6 antikoerper, Tnfrsf6 antikoerper, lpr antikoerper, Fas cell surface death receptor antikoerper, Fas (TNF receptor superfamily member 6) antikoerper, FAS antikoerper, Fas antikoerper, fas antikoerper

Hintergrund

Synonyms: APT1, CD95, FAS1, APO-1, FASTM, ALPS1A, TNFRSF6, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor, FAS
Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

Gen-ID

355

UniProt

P25445

Pathways

p53 Signalweg, Apoptose, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity