HOPX Antikörper (AA 25-73)

Produktnummer ABIN1387281

Dieser Anti-HOPX Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von HOPX in WB, IF (p) und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für HOPX Antikörper (AA 25-73) (ABIN1387281)

Target: HOPX (HOP Homeobox (HOPX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOPX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HOPX Antikörper

Bindungsspezifität: AA 25-73

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOPX/LAGY

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HOPX

Target: HOPX (HOP Homeobox (HOPX))

Andere Bezeichnung: LAGY

Hintergrund:

Synonyms: HOD, HOP, OB1, LAGY, TOTO, CAMEO, NECC1, SMAP31, Homeodomain-only protein, Lung cancer-associated Y protein, Not expressed in choriocarcinoma protein 1, Odd homeobox protein 1, HOPX

Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.

Gen-ID: 84525

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation