UGCG Antikörper (AA 31-98)

Produktnummer ABIN1386872

Der Kaninchen Polyklonal Anti-UGCG-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, UGCG in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für UGCG Antikörper (AA 31-98) (ABIN1386872)

Target: UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGCG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-UGCG Antikörper

Bindungsspezifität: AA 31-98

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human UGCG

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu UGCG

Target: UGCG (UDP-Glucose Ceramide Glucosyltransferase (UGCG))

Andere Bezeichnung: UGCG

Hintergrund:

Synonyms: CEGT_HUMAN, Ceramide glucosyltransferase, GCS, GLCT 1, GLCT-1, GLCT1, Glucosylceramide synthase, UDP glucose ceramide glucosyltransferase, UDP glucose N acylsphingosine D glucosyltransferase, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, Ugcg.

Background: Glucosylceramide synthase (GCS), also designated ceramide glucosyltransferase, belongs to the glycosyltransferase 2 family. It is a widely expressed integral membrane protein encoded by UGCG. The enzyme can be found in the plasma membrane of all eukaryotic cells, and a significant concentration of glucosylceramide synthase activity has been reported in the Golgi complex. Glucosylceramide synthase catalyzes the first glycosylation step in glycosphingolipid biosynthesis and functions as a glucosyltransferase and flippase in the transfer of glucose to ceramide. Glucosylceramide synthase operates in cell recognition, cell proliferation and differentiation, immune recognition and signal transduction. The regulation of ceramide levels through glucosylceramide synthase has been associated with the induction of apoptosis and notable research implicates this relationship with drug-induced apoptosis in a variety of cell types.