HTR7 Antikörper (AA 51-150)

Produktnummer ABIN1386673

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HTR7 in WB, ELISA, IHC (p), IF (cc), IF (p), ICC und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Ratte und Maus.

Kurzübersicht für HTR7 Antikörper (AA 51-150) (ABIN1386673)

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HTR7 Antikörper

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Maus, Ratte

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HTR7

Target: HTR7 (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled) (HTR7))

Andere Bezeichnung: 5HT7 Receptor/SR-7

Hintergrund:

Synonyms: HT 7, 5 HT X, 5 hydroxytryptamine serotonin receptor 7 adenylate cyclase coupled, 5 hydroxytryptamine serotonin receptor 7, 5 hydroxytryptamine receptor 7, 5-HT-7, 5-HT-X, 5-HT7, 5-hydroxytryptamine receptor 7, 5HT7, 5HT7R_HUMAN, HTR7, Serotonin 5 HT 7 receptor, Serotonin receptor 7.

Background: Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.

Gen-ID: 3363

UniProt: P34969

Pathways: JAK-STAT Signalweg