Serotonin Receptor 5A Antikörper (AA 1-110)

Produktnummer ABIN1386672

Dieses Anti-Serotonin Receptor 5A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Serotonin Receptor 5A in ELISA, IHC (p), ICC, IF (cc), IF (p) und IHC (fro). Geeignet für Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für Serotonin Receptor 5A Antikörper (AA 1-110) (ABIN1386672)

Target: Serotonin Receptor 5A (HTR5A)

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 5A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Serotonin Receptor 5A Antikörper

Bindungsspezifität: AA 1-110

Kreuzreaktivität: Ratte

Homologie: Human,Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HT5A receptor/SR-5A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Serotonin Receptor 5A Antikörper (ABIN1386672)

García-Pedraza, Hernández-Abreu, Morán, Carretero, García-Domingo, Villalón: "Role of peripheral 5-HT5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats." in: Scientific reports, Vol. 10, Issue 1, pp. 19358, (2021) (PubMed).

Details zu Serotonin Receptor 5A

Target: Serotonin Receptor 5A (HTR5A)

Andere Bezeichnung: 5HT5A receptor/SR-5A

Hintergrund:

Synonyms: HTR5A, 5 HT 5A, 5 hydroxytryptamine 5A receptor, 5-HT-5, 5-HT-5A, 5-HT5A, 5-hydroxytryptamine receptor 5A, 5HT5A, 5HT5A_HUMAN, HTR5A, Serotonin receptor 5A.

Background: SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134) is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus. Serotonin receptors include SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F. Subtypes within the SR-2 group include SR-2A, -2B and -2C. Subtypes within the SR-5 group include SR-5A and -5B. SR receptors can couple to G proteins that act on either adenylate cyclase or phospholipase C (PLC). The SR-3 class of receptors are ion channels.32234.

Pathways: JAK-STAT Signalweg