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mGluR1 + mGluR5 Antikörper (Glutamate Receptor, Metabotropic 5/1) AA 501-600 Primary Antibody

mGluR1/5 Reaktivität: Maus ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1386658
$352.31
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 4 bis 6 Werktagen
  • Target See all mGluR1 + mGluR5 (mGluR1/5) products
    mGluR1 + mGluR5 (mGluR1/5)
    Bindungsspezifität
    • 16
    • 5
    • 3
    • 2
    • 1
    AA 501-600
    Reaktivität
    • 24
    • 22
    • 22
    • 2
    Maus
    Wirt
    • 18
    • 8
    Kaninchen
    Klonalität
    • 18
    • 8
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser mGluR1 + mGluR5 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 13
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Homologie
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    mGluR1 + mGluR5 (mGluR1/5)
    Andere Bezeichnung
    MGLUR1 + MGLUR5 (mGluR1/5 Produkte)
    Hintergrund

    Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a. The Group-II receptors in include mGluR2 and mGluR3.

    Subcellular location: Cell membrane

    Synonyms: MGLUR1+MGLUR5, GPRC1A, GPRC1E, GRM1, GRM1A, GRM5, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 5, mGlu1, mGlu5, MGLUR1, MGLUR1A, MGLUR5, MGLUR5B, GRM1_HUMAN, GRM5_HUMAN.

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