NETO2 Antikörper (AA 151-250)

Produktnummer ABIN1386596

Der Kaninchen Polyklonal anti-NETO2 Antikörper wird verwendet zum Nachweis von NETO2 in Proben von Human. Er wurde validiert für ELISA, IF (cc), IF (p), IHC (p), IHC (fro) und ICC.

Kurzübersicht für NETO2 Antikörper (AA 151-250) (ABIN1386596)

Target: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NETO2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-NETO2 Antikörper

Bindungsspezifität: AA 151-250

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NETO2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NETO2

Target: NETO2 (Neuropilin (NRP) and Tolloid (TLL)-Like 2 (NETO2))

Andere Bezeichnung: NETO2

Hintergrund:

Synonyms: Brain specic transmembrane protein, Brain specic transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2, Brain-specic transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2, BTCL2, FLJ10430, FLJ14724, FLJ90456, NEOT2, NETO 2, Neto2, NETO2_HUMAN, Neuropilin NRP and tolloid TLL like 2, Neuropilin and tolloid like protein 2, Neuropilin and tolloid-like protein 2.

Background: NETO2 is a 525 amino acid single-pass type I membrane protein that contains two CUB domains and one LDL-receptor class A domain. Expressed as multiple alternatively spliced isoforms, NETO2 is thought to play a role in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. The gene encoding NETO2 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.