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AP2M1 Antikörper (pThr156)

Dieses Anti-AP2M1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AP2M1 in WB, ELISA, IF (cc), IF (p), IHC (p), ICC und IHC (fro). Geeignet für Maus.
Produktnummer ABIN1386471

Kurzübersicht für AP2M1 Antikörper (pThr156) (ABIN1386471)

Target

Alle AP2M1 Antikörper anzeigen
AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Reaktivität

  • 78
  • 41
  • 25
  • 4
  • 2
  • 2
  • 1
  • 1
Maus

Wirt

  • 82
  • 11
  • 2
Kaninchen

Klonalität

  • 75
  • 20
Polyklonal

Konjugat

  • 45
  • 7
  • 7
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser AP2M1 Antikörper ist unkonjugiert

Applikation

  • 69
  • 36
  • 25
  • 25
  • 23
  • 12
  • 11
  • 7
  • 6
  • 5
  • 5
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 15
    • 15
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr156

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Sheep,Chicken

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human AP2M1 around the phosphorylation site of Thr156

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

    Andere Bezeichnung

    AP2M1

    Hintergrund

    Synonyms: AP2M1 phospho T156, p-AP2M1phospho T156, Adaptin mu 1, Clathrin coat associated protein AP50, Adapter-related protein complex 2 mu subunit, Adaptin-mu2, Adaptor protein complex AP 2 subunit mu, Adaptor protein complex AP-2 subunit mu, Adaptor related protein complex 2 mu 1 subunit, AP 2 mu 2 chain, AP-2 complex subunit mu, AP-2 mu chain, Ap2m1, AP2M1_HUMAN, AP50, CLAPM1, Clathrin adaptor complex AP2 mu subunit, Clathrin assembly protein complex 2 medium chain, Clathrin associated/assembly/adaptor protein medium 1, Clathrin coat adaptor protein AP50, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, HA2 50 kDa subunit, mu2 antibody, Plasma membrane adaptor AP-2 50 kDa protein.

    Background: Adaptins are heterotetrameric subunits of adaptors, which are complexes involved in the formation of Clathrin-coated pits for vesicle-mediated endocytosis. Clathrin and its associated heterotetrameric protein complexes make up the main protein components of the coat surrounding the cytoplasmic face of coated vesicles. The Adaptin family, comprising a, b, and g classes, is also responsible for the transport of ligand-receptor complexes from plasma membranes and the trans-Golgi network to lysosomes. Two main types of adaptor proteins (APs), AP-1 and AP-2, are found in Clathrin-coated structures located at the Golgi complex and the plasma membrane of mammalian cells, respectively. Adaptor protein complex 2 (AP-2) is composed of two large Adaptins (a1A/AP2A1 and b1/AP2B1), a medium Adaptin (m2/AP-2m1) and a small Adaptin (s2 long/AP2S1). AP-2m1, a 435 amino acid protein, links Clathrin to receptors in coated vesicles.

    Pathways

    EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation, SARS-CoV-2 Protein Interaktom
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