FAM84A Antikörper (AA 151-250)

Produktnummer ABIN1386304

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FAM84A in ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) und ICC. Er zeigt eine Reaktivität gegenüber Ratte und wurde in 1 Publikation erwähnt.

Kurzübersicht für FAM84A Antikörper (AA 151-250) (ABIN1386304)

Target: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM84A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-FAM84A Antikörper

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Chicken,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NSE1/FAM84A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-FAM84A Antikörper (ABIN1386304)

Wang, Xu, Qin, Wang, Ma, Luo, Zhang: "Myocardin-related transcription factor-A is a key regulator in retinoic acid-induced neural-like differentiation of adult bone marrow-derived mesenchymal stem cells." in: Gene, Vol. 523, Issue 2, pp. 178-86, (2013) (PubMed).

Details zu FAM84A

Target: FAM84A (Family with Sequence Similarity 84, Member A (FAM84A))

Andere Bezeichnung: Nse1/Fam84a

Hintergrund:

Synonyms: FAM 84A, Family with sequence similarity 84 member A, family with sequence similarity 84, member A, FLJ35392, Neurologic sensory protein 1, Neurological/sensory 1, NSE 1, NSE1, PP11517, Protein FAM84A, Protein NSE1.

Background: FAM84A is a 292 amino acid protein that belongs to the FAM84 family of proteins. Predominantly expressed in testis, FAM84A shares 44 % amino acid identity with the related protein FAM84B. FAM84A localizes to a subcellular membrane region where there is no contact between neighboring cells and is believed to play a role in cell morphology and motility. More specifically, the expression of FAM84A increases cell motility. Two FAM84A isoforms are expressed due to alternative splicing events. Isoform 2 can be phosphorylated on various serine residues and this phosphorylation is associated with cellular morphology. FAM84A is upregulated in colorectal cancer, lung cancer, pancreatic cancer, cholangiocarcinoma and bladder cancer tissues. Via its ability to increase cell motility, FAM84A may contribute to the invasion and metastasis of cancer cells.

Gen-ID: 3859