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DUOX1 Antikörper (AA 1-100)

Dieses Anti-DUOX1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DUOX1 in ELISA, WB, IHC (p), ICC, IF (cc), IF (p) und IHC (fro). Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN1386159

Kurzübersicht für DUOX1 Antikörper (AA 1-100) (ABIN1386159)

Target

Alle DUOX1 Antikörper anzeigen
DUOX1 (Dual Oxidase 1 (DUOX1))

Reaktivität

Human, Maus, Ratte

Wirt

  • 4
  • 2
  • 1
Kaninchen

Klonalität

  • 7
Polyklonal

Konjugat

  • 7
Dieser DUOX1 Antikörper ist unkonjugiert

Applikation

ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1-100

    Kreuzreaktivität

    Human, Maus, Ratte

    Homologie

    Dog,Cow,Sheep,Pig,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human DUOX1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Wakatsuki, Furuno, Ohshima, Araki: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." in: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).

  • Target

    DUOX1 (Dual Oxidase 1 (DUOX1))

    Andere Bezeichnung

    DUOX1

    Hintergrund

    Synonyms: Dual oxidase 1, Dual oxidase 1 precursor, DUOX1, EC 1.11.1, EC 1.6.3.1, Flavoprotein NADPH oxidase, Large NOX 1, LNOX1, Long NOX 1, MGC138840, MGC138841, NADPH thyroid oxidase 1, Nicotinamide adenine dinucleotide phosphate oxidase, NOXEF1, THOX1, Thyroid oxidase 1, DUOX1_HUMAN.

    Background: Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid, trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.

    Gen-ID

    53905
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