SGK1 Antikörper

Produktnummer ABIN1385850

Produktdetails anti-SGK1 Antikörper

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Rind (Kuh), Hund, Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SGK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SGK1

Target: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Andere Bezeichnung: SGK1 (SGK1 Produkte)

Synonyme: SGK antikoerper, Sgk antikoerper, sgk-B antikoerper, sgk2 antikoerper, cb1083 antikoerper, sgk antikoerper, wu:fc20a09 antikoerper, sgk-A antikoerper, sgk1 antikoerper, sgk1-a antikoerper, sgk1-b antikoerper, serum/glucocorticoid regulated kinase 1 antikoerper, Serine/threonine-protein kinase sgk-1 antikoerper, serum/glucocorticoid regulated kinase 1 S homeolog antikoerper, serum/glucocorticoid regulated kinase 1 L homeolog antikoerper, SGK1 antikoerper, Sgk1 antikoerper, sgk-1 antikoerper, sgk1.S antikoerper, sgk1 antikoerper, sgk1.L antikoerper

Hintergrund:

Synonyms: Serum/glucocorticoid regulated kinase 1, SGK 1, SGK-1, Serine/threonine protein kinase SGK, Serine/threonine protein kinase Sgk1, Serum and glucocorticoid regulated kinase, Serum/glucocorticoid regulated kinase, SGK 1, SGK.

Background: SGK1 is a protein kinase that plays an important role in cellular stress response. SGK1 activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels of SGK1 and activity may contribute to conditions such as hypertension and diabetic nephropathy. This protein also mediates cell survival signals, as it has been shown to phosphorylate and negatively regulate the pro apoptotic FOXO3A protein. Ser 422 is a critical site on the protein and may be involved in its activation.

Molekulargewicht: 49kDa

Pathways: MAPK Signalweg, Notch Signalweg, Steroid Hormone Mediated Signaling Pathway