beta 2 Defensin Antikörper (AA 24-64)

Produktnummer ABIN1385259

Produktdetails anti-beta 2 Defensin Antikörper

Target: beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))

Bindungsspezifität: AA 24-64

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser beta 2 Defensin Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Ratte

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human beta 2 Defensin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-beta 2 Defensin Antikörper (ABIN1385259)

Al-Samadi, Salem, Ainola, Hietanen, Häyrinen-Immonen, Konttinen: "Increased beta 2 defensin in recurrent aphthous ulcer." in: Oral diseases, (2014) (PubMed).

Details zu beta 2 Defensin

Target: beta 2 Defensin (BD-2) (Defensin beta 2 (BD-2))

Abstract: BD-2 Produkte

Synonyme: BD-2 antikoerper, BD-4 antikoerper, DEFB-4 antikoerper, hBD-4 antikoerper, BD2 antikoerper, DEFB2 antikoerper, defensin beta 2 antikoerper, defensin beta 104B antikoerper, beta defensin 2 antikoerper, Defb2 antikoerper, DEFB104B antikoerper, SBD2 antikoerper

Hintergrund:

Synonyms: BD-2, SAP1, DEFB2, DEFB4, HBD-2, DEFB-2, DEFB12, Beta-defensin 4A, Beta-defensin 2, Defensin, beta 2, Skin-antimicrobial peptide 1, DEFB4A

Background: Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways

Gen-ID: 1673

UniProt: O15263