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RPGRIP1L Antikörper (AA 41-140)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RPGRIP1L in WB, ELISA, IF (cc), IF (p), ICC, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1385221

Kurzübersicht für RPGRIP1L Antikörper (AA 41-140) (ABIN1385221)

Target

Alle RPGRIP1L Antikörper anzeigen
RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

Reaktivität

  • 19
  • 2
  • 2
Human

Wirt

  • 18
  • 1
Kaninchen

Klonalität

  • 19
Polyklonal

Konjugat

  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RPGRIP1L Antikörper ist unkonjugiert

Applikation

  • 19
  • 12
  • 12
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 14
    • 1
    • 1
    • 1
    • 1
    AA 41-140

    Homologie

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human RPGRIP1L

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    RPGRIP1L (RPGRIP1-Like (RPGRIP1L))

    Andere Bezeichnung

    RPGRIP1L

    Hintergrund

    Synonyms: CORS 3, CORS3, Fantom, FTM, JBTS 1, JBTS 7, JBTS1, JBTS7, Joubert syndrome 1, Joubert syndrome 7, Meckel syndrome, type 1, RPGRIP1-like, Meckel syndrome, type 5, MKS 5, MKS5, NPHP 8, NPHP8, nephrocystin 8, Protein fantom, Retinitis pigmentosa GTPase regulator interacting protein 1 like, RPGR interacting protein 1 like protein, RPGRIP1 like protein, FTM_HUMAN.

    Background: RPGRIP1L is a 1,315 amino acid protein that belongs to the RPGRIP1 family and is thought to function in programmed cell death, craniofacial development and formation of the left-right axis. Existing as two alternatively spliced isoforms that localize to the cytoplasm, cytoskeleton, centrosome and cilium basal body, RPGRIP1L interacts with nephrocystin-4 and is moderately expressed in brain, retina and kidney. Containing two C2 domains, RPGRIP1L is encoded by a gene that maps to human chromosome 16q12.2. Defects in the gene encoding RPGRIP1L are the cause of Joubert syndrome type 7 (JBTS7), COACH syndrome (COACHS) and Meckel syndrome type 5 (MKS5).

    Pathways

    DNA Replication, Regulation of G-Protein Coupled Receptor Protein Signaling, Synthesis of DNA
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