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PCSK1N Antikörper (Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor) AA 34-130 Primary Antibody

PCSK1N Reaktivität: Human ELISA, ICC, IF (cc), IF (p), IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1385206
$374.00
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 4 bis 6 Werktagen
  • Target Alle PCSK1N Antikörper anzeigen
    PCSK1N
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 34-130
    Reaktivität
    • 17
    • 17
    • 9
    • 1
    • 1
    • 1
    Human
    Wirt
    • 18
    • 5
    • 1
    Kaninchen
    Klonalität
    • 21
    • 3
    Polyklonal
    Konjugat
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCSK1N Antikörper ist unkonjugiert
    Applikation
    ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PROSAAS
    Isotyp
    IgG
  • Applikationshinweise
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PCSK1N
    Andere Bezeichnung
    PROSAAS (PCSK1N Produkte)
    Synonyme
    PROSAAS, SAAS, Saas, AI848336, KEP, PEN, PEN19, PEN20, Pan3, SAASCT, bLEN, lLEN, proSAAS, proprotein convertase subtilisin/kexin type 1 inhibitor, PCSK1N, Pcsk1n
    Hintergrund

    PCSK1N is a 260 amino acid protein that is both secreted and localized to the trans-Golgi network. Expressed in pancreas and brain, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition. The gene encoding PCSK1N maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

    Subcellular location: Cytoplasm, Secreted

    Synonyms: b-LEN, b-PEN-LEN, b-SAAS, Big LEN, granin like neuroendocrine peptide, l-LEN, l-SAAS, N-proSAAS, PCSK1_HUMAN, Pcsk1n, pro-SAAS, Proprotein convertase 1 inhibitor, Proprotein convertase subtilisin/kexin type 1 inhibitor, PROSAAS, SAAS, SAAS CT1-49, SAAS CT25-40.

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