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UBXN6 Antikörper

UBXN6 Reaktivität: Human WB, IF, IP Wirt: Maus Monoclonal 5C3-1 unconjugated
Produktnummer ABIN1381743
  • Target Alle UBXN6 Antikörper anzeigen
    UBXN6 (UBX Domain Protein 6 (UBXN6))
    Reaktivität
    • 28
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 27
    • 1
    Maus
    Klonalität
    • 27
    • 1
    Monoklonal
    Konjugat
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser UBXN6 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 19
    • 18
    • 4
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Spezifität
    Detects both isoforms
    Keine Kreuzreaktivität
    Maus
    Aufreinigung
    purified
    Immunogen
    recombinant protein purified from bacteria
    Klon
    5C3-1
    Isotyp
    IgG1
    Top Product
    Discover our top product UBXN6 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.5 % PBS, 50 % glycerol, 0.1 % BSA
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C
    Informationen zur Lagerung
    short term: 2 °C - 8 °C, long term: -20 °C
  • Target
    UBXN6 (UBX Domain Protein 6 (UBXN6))
    Andere Bezeichnung
    UBXD1 (Full Length and Short Isoform) (UBXN6 Produkte)
    Synonyme
    Ubxd1 antikoerper, UBXD1 antikoerper, UBXDC2 antikoerper, 1200008L11Rik antikoerper, 2210415J11Rik antikoerper, AU040909 antikoerper, Ubxdc2 antikoerper, UBX domain protein 6 antikoerper, Ubxn6 antikoerper, UBXN6 antikoerper
    Hintergrund
    P97 is a highly abundant and conserved member of the AAA family of ATPase. It has been termed an ubiquitin selective chaperone as it functions within the ubiquitin and/or proteasome pathway. p97 does not interact with ubiquitinated substrates on its own, but requires specific adapters that interact with ubiquitinated substrates and p97 and recruits p97 to substrates. One family of adapters contains a UBX domain, which has been shown with certain adapters to function as a p97-binding module. UBXD1 is a UBX domain containing protein and p97 adapter. This adapter is unique in that it does not harbor an ubiquitin association domain and binds p97 via its PUG domain (another p97 binding motif). Two isoforms of UBXD1 are produced in cells, a full-length form of approximately 54 kDa, and an alternatively spliced variant that lacks the amino-terminal translational start site, and encodes a 47 kDa protein that is derived from an internal translational initiation site. UBXD1 expression at the RNA level has been shown to trend lower in poor prognostic cancers, including those of the breast and prostate.
    UniProt
    Q9BZV1
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