VCAM1 Antikörper (FITC)

Produktnummer ABIN135717

Dieses Anti-VCAM1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von VCAM1 in FACS. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für VCAM1 Antikörper (FITC) (ABIN135717)

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VCAM1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: 1-G11B1

Produktdetails anti-VCAM1 Antikörper (FITC)

Spezifität: Human/Porcine CD106, Mr 110 kDa

Produktmerkmale: Mouse Anti-Human CD106-FITC

Immunogen: Unknown

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB-NR - Reported in literature , ELISA - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-VCAM1 Antikörper (FITC) (ABIN135717)

Silva-Pedrosa, Campos, Fernandes, Silva, Calçada, Marote, Martinho, Veiga, Rodrigues, Salgado, Ferreira: "Cerebral Malaria Model Applying Human Brain Organoids." in: Cells, Vol. 12, Issue 7, (2023) (PubMed).

Details zu VCAM1

Target: VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))

Andere Bezeichnung: CD106

Hintergrund: CD106, also known as INCAM-1, is a 100-110 kDa vascular adhesion cell adhesion molecule-1 (VCAM-1) that is member of the immunoglobulin superfamily. CD106 is expressed predominantly on cytokine-activated vascular endothelium but has also been identified on interfollicular dendritic cells, some macrophages and bone marrow stromal cells. Endothelial CD106 binds the integrins 41 (CD49d/CD29, VLA-4) and 47 and contributes to extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, particularly at sites of inflammation. Unlike the 2 integrins, the CD106-VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endothelium as well as their subsequent arrest and firm adhesion. CD106 expressed on non-vascular tissues has been implicated in the interaction of hematopoietic progenitors with bone marrow stromal cells, B cell binding to follicular dendritic cells, costimulation of T cells, and embryonic development.

Pathways: Carbohydrate Homeostasis