CD86 Antikörper

Produktnummer ABIN135433

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CD86 in FACS, IP, ELISA, IHC (fro), BR, Sep und CMCD. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CD86 Antikörper (ABIN135433)

Target: CD86

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD86 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Separation (Sep), Complement Mediated Cell Depletion (CMCD)

Klon: 2D10

Produktdetails anti-CD86 Antikörper

Verwendungszweck: Rat Anti-Mouse CD86-LE/AF

Spezifität: Mouse CD86, Mr 80 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD86 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, separation, CMCD, and blocking assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: Mouse B cell lymphoma cell line 5C2

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86

Hintergrund: CD86/B7-2 is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80/B7-1, CD86 participates in T cell costimulation via interaction with CD28 and CD152/CTLA-4. It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes and dendritic cells. Since CD86/B7-2 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.

Gen-ID: 12524

UniProt: P42082

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation