Endoglin Antikörper

Produktnummer ABIN135375

Produktdetails anti-Endoglin Antikörper

Target: Endoglin (ENG)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Endoglin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: Mouse CD105, Mr 90 kDa

Produktmerkmale: Rat Anti-Mouse CD105-UNLB

Aufreinigung: Purified

Immunogen: Inflamed mouse skin

Klon: MJ7-18

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , WB - Reported in literature , Sep - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells PACBLU conjugate 1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: CD105 (ENG Produkte)

Hintergrund: CD105/endoglin is a disulfide-linked type II transmembrane homodimer that is predominantly expressed on vascular endothelial cells. It is also found on pre-erythroblasts, macrophages and lymphoid and myeloid leukemic cells. Both mouse and human CD105 exhibit > 70 % sequence homology in their cytoplasmic domains with type III transforming growth factor (TGF) receptor. CD105 has been shown to be one of several receptors for the various isoforms of TGF, which in turn is one of a family of proteins involved in regulation of cell differentiation, migration of cells and control of the immune response.