CD86 Antikörper

Produktnummer ABIN135277

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CD86 in FACS, IP, IHC (fro) und BR. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CD86 Antikörper (ABIN135277)

Target: CD86

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD86 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Klon: GL1

Produktdetails anti-CD86 Antikörper

Verwendungszweck: Rat Anti-Mouse CD86-LE/AF

Spezifität: Mouse CD86, Mr 80 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD86 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: LPS-activated CBA/Ca mouse spleen B cells

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86

Hintergrund: CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80/B7-1, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA-4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.

Gen-ID: 12524

UniProt: P42082

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation