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CD80 Antikörper

CD80 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 1G10 unconjugated
Produktnummer ABIN135272
  • Target Alle CD80 Antikörper anzeigen
    CD80
    Reaktivität
    • 138
    • 107
    • 44
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 87
    • 71
    • 23
    • 18
    • 16
    • 1
    • 1
    Ratte
    Klonalität
    • 137
    • 77
    • 2
    Monoklonal
    Konjugat
    • 85
    • 18
    • 17
    • 15
    • 13
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD80 Antikörper ist unkonjugiert
    Applikation
    • 127
    • 93
    • 69
    • 35
    • 34
    • 22
    • 14
    • 13
    • 13
    • 13
    • 11
    • 11
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD80, Mr 52-55 kDa
    Produktmerkmale
    Rat Anti-Mouse CD80-LE/AF
    Aufreinigung
    Ion exchange
    Endotoxin-Niveau
    Low endotoxin
    Immunogen
    Activated 5C2 cells
    Klon
    1G10
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD80 Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Kommentare

    In vivo and in vitro blocking of ligand binding

    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    Konservierungsmittel
    Azide free
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Target
    CD80
    Andere Bezeichnung
    CD80 (CD80 Produkte)
    Synonyme
    B7 antikoerper, B7-1 antikoerper, B7.1 antikoerper, BB1 antikoerper, CD28LG antikoerper, CD28LG1 antikoerper, LAB7 antikoerper, B71 antikoerper, Cd28l antikoerper, Ly-53 antikoerper, Ly53 antikoerper, MIC17 antikoerper, TSA1 antikoerper, CD80 molecule antikoerper, Cd80 molecule antikoerper, CD80 antigen antikoerper, CD80 antikoerper, Cd80 antikoerper
    Hintergrund
    CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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