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CD80 Antikörper

CD80 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 1G10 unconjugated
Produktnummer ABIN135268
  • Target Alle CD80 Antikörper anzeigen
    CD80
    Reaktivität
    • 138
    • 108
    • 44
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 87
    • 71
    • 23
    • 18
    • 17
    • 1
    • 1
    Ratte
    Klonalität
    • 138
    • 77
    • 2
    Monoklonal
    Konjugat
    • 86
    • 18
    • 17
    • 15
    • 13
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD80 Antikörper ist unkonjugiert
    Applikation
    • 128
    • 93
    • 69
    • 35
    • 34
    • 22
    • 14
    • 13
    • 13
    • 13
    • 11
    • 11
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD80, Mr 52-55 kDa
    Produktmerkmale
    Rat Anti-Mouse CD80-UNLB
    Aufreinigung
    Purified
    Immunogen
    Activated 5C2 cells
    Klon
    1G10
    Isotyp
    IgG2a
    Top Product
    Discover our top product CD80 Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Kommentare

    In vivo and in vitro blocking of ligand binding

    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    Konservierungsmittel
    Without preservative
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C
  • Target
    CD80
    Andere Bezeichnung
    CD80 (CD80 Produkte)
    Synonyme
    B7 antikoerper, B7-1 antikoerper, B7.1 antikoerper, BB1 antikoerper, CD28LG antikoerper, CD28LG1 antikoerper, LAB7 antikoerper, B71 antikoerper, Cd28l antikoerper, Ly-53 antikoerper, Ly53 antikoerper, MIC17 antikoerper, TSA1 antikoerper, CD80 molecule antikoerper, Cd80 molecule antikoerper, CD80 antigen antikoerper, CD80 antikoerper, Cd80 antikoerper
    Hintergrund
    CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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