Transferrin Receptor Antikörper

Produktnummer ABIN135263

Der Ratte Monoklonal anti-Transferrin Receptor Antikörper wird verwendet zum Nachweis von Transferrin Receptor in Proben von Maus. Er wurde validiert für FACS, WB, IP, ICC, BR, DD und Sep.

Kurzübersicht für Transferrin Receptor Antikörper (ABIN135263)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Blocking Reagent (BR), Drug Delivery (DD), Separation (Sep)

Klon: RI7217

Produktdetails anti-Transferrin Receptor Antikörper

Verwendungszweck: Rat Anti-Mouse CD71-LE/AF

Spezifität: Mouse CD71, Mr 95 kDa

Produktmerkmale: Low Endotoxin/Azide Free Anti-Mouse CD71 antibody for use in flow cytometry, immunocytochemistry, western blotting, immunoprecipitation, blocking, separation, and drug delivery assays.

Endotoxin-Niveau: Low Endotoxin

Immunogen: DMSO induced Friend erythroleukemia 745.6

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Konservierungsmittel: Azide free

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71

Hintergrund: CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.

Gen-ID: 22042

UniProt: Q62351

Pathways: Transition Metal Ion Homeostasis