Transferrin Receptor Antikörper (FITC)

Produktnummer ABIN135260

Der Ratte Monoklonal Anti-Transferrin Receptor-Antikörper wurde für FACS validiert. Er ist geeignet, Transferrin Receptor in Proben von Maus zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Transferrin Receptor Antikörper (FITC) (ABIN135260)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: RI7217

Produktdetails anti-Transferrin Receptor Antikörper (FITC)

Spezifität: Mouse CD71, Mr 95 kDa

Produktmerkmale: Rat Anti-Mouse CD71-FITC

Aufreinigung: Ion exchange column

Immunogen: DMSO induced Friend erythroleukemia 745.6

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Sep - Reported in literature , Drug Delivery - Reported in literature
• Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg in 1.0 mL of PBS/Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-Transferrin Receptor Antikörper (FITC) (ABIN135260)

Balmus, Karp, Ng, Jackson, Adams, McIntyre: "A high-throughput in vivo micronucleus assay for genome instability screening in mice." in: Nature protocols, Vol. 10, Issue 1, pp. 205-15, (2015) (PubMed).

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71

Hintergrund: CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens, presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron, which is essential for many metabolic pathways, through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor chain.

Pathways: Transition Metal Ion Homeostasis