CD3 epsilon Antikörper

Produktnummer ABIN135085

Dieser Hamster Monoklonal Antikörper detektiert spezifisch CD3 epsilon in FACS. Es zeigt Reaktivität gegenüber Proben von Maus.Es wurde in 1 Publikation zitiert.

Kurzübersicht für CD3 epsilon Antikörper (ABIN135085)

Target: CD3 epsilon (CD3E)

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD3 epsilon Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 145-2C11

Produktdetails anti-CD3 epsilon Antikörper

Spezifität: Mouse CD3, Mr 25 kDa

Produktmerkmale: Hamster Anti-Mouse CD3e-UNLB

Aufreinigung: Purified

Immunogen: H-2Kb-specific murine cytotoxic T-lymphocyte (CTL) clone BM10-37

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

• Applications: FC - Quality tested , IHC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Depletion - Reported in literature , Activ - Reported in literature , CMCD - Reported in literature
• Working Dilutions: Flow Cytometry FITC conjugate 3 g/106 cells BIMA and AF488 conjugates 1 g/106 cells PE, APC, SPRD, and AF647 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 l

Kommentare:

In vitro depletion of CD3+ cells, In vitro activation of T cells

Probenmenge: 1 mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Konservierungsmittel: Without preservative

Handhabung: Each reagent is stable for the period shown on the bottle label if stored as directed.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C

Referenzen für anti-CD3 epsilon Antikörper (ABIN135085)

Ershaid, Sharon, Doron, Raz, Shani, Cohen, Monteran, Leider-Trejo, Ben-Shmuel, Yassin, Gerlic, Ben-Baruch, Pasmanik-Chor, Apte, Erez: "NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).

Details zu CD3 epsilon

Target: CD3 epsilon (CD3E)

Andere Bezeichnung: CD3e

Hintergrund: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation.

Pathways: T-Zell Rezeptor Signalweg, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway