Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

VCAM1 Antikörper

VCAM1 Reaktivität: Maus FACS Wirt: Ratte Monoclonal M-K-2 unconjugated
Produktnummer ABIN135074
  • Target Alle VCAM1 Antikörper anzeigen
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Reaktivität
    • 138
    • 107
    • 57
    • 25
    • 15
    • 8
    • 8
    • 4
    • 3
    • 1
    Maus
    Wirt
    • 96
    • 76
    • 44
    • 5
    • 1
    • 1
    Ratte
    Klonalität
    • 130
    • 91
    • 1
    Monoklonal
    Konjugat
    • 98
    • 27
    • 25
    • 14
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VCAM1 Antikörper ist unkonjugiert
    Applikation
    • 115
    • 109
    • 55
    • 43
    • 40
    • 35
    • 27
    • 26
    • 25
    • 16
    • 16
    • 13
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Mouse CD106, Mr 100-110 kDa
    Produktmerkmale
    Rat Anti-Mouse CD106-LE/AF
    Endotoxin-Niveau
    Low endotoxin
    Immunogen
    BALB/3T3 and +/+2.4 cells
    Klon
    M-K-2
    Isotyp
    IgG1
    Top Product
    Discover our top product VCAM1 Primärantikörper
  • Applikationshinweise
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , WB - Reported in literature , Adhesion - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE conjugate 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    Probenmenge
    1 mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    Konservierungsmittel
    Azide free
    Handhabung
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • Gilchrist, Kinchesh, Zarghami, Khrapitchev, Sibson, Kersemans, Smart: "Improved detection of molecularly targeted iron oxide particles in mouse brain using B0 field stabilised high resolution MRI." in: Magnetic resonance imaging, Vol. 67, pp. 101-108, (2020) (PubMed).

    Zarghami, Khrapitchev, Perez-Balderas, Soto, Larkin, Bau, Sibson: "Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles." in: International journal of nanomedicine, Vol. 13, pp. 4345-4359, (2018) (PubMed).

  • Target
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Andere Bezeichnung
    CD106 (VCAM1 Produkte)
    Synonyme
    CD106 antikoerper, INCAM-100 antikoerper, Vcam-1 antikoerper, VCAM1B antikoerper, fi76d06 antikoerper, wu:fi76d06 antikoerper, zgc:158875 antikoerper, VCAM1 antikoerper, vascular cell adhesion molecule 1 antikoerper, vascular cell adhesion molecule 1b antikoerper, VCAM1 antikoerper, Vcam1 antikoerper, vcam1b antikoerper, VCAM-1 antikoerper
    Hintergrund
    VCAM-1 is an adhesion molecule and a major mediator of the inflammatory response. It is expressed on activated microvascular endothelial cells in response to signals arising from immune responses in infection, graft rejection, tumor recognition and killing. The complementary binding ligand for VCAM-1 is VLA-4/CD49d. In addition to VCAM-1, VLA-4 also recognizes the extracellular matrix molecule fibronectin. This pairing of VCAM-1 and VLA-4 is able to provide a second signal (i.e., non-antigen specific) for T cell stimulation, such as that seen in transplantation. The monoclonal antibody MK-2 has been used in transplant studies to suppress cardiac rejection and induce long-term cardiac graft survival. In addition to inflammatory responses, VCAM-1 has a significant role in hemopoiesis through its ability to retain lymphocyte and myeloid precursors on stromal cells in the marrow and lymphoid organs. CD106/VCAM-1 exists as an integral membrane protein.
    Pathways
    Carbohydrate Homeostasis
Sie sind hier:
Kundenservice