HMGB1 Antikörper (AA 1-215)

Produktnummer ABIN1326935

Der Maus Monoklonal Anti-HMGB1-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, HMGB1 in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für HMGB1 Antikörper (AA 1-215) (ABIN1326935)

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HMGB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1E6-E10

Produktdetails anti-HMGB1 Antikörper

Bindungsspezifität: AA 1-215

Verwendungszweck: Mouse monoclonal antibody raised against a full-length recombinant HMGB1.

Sequenz: MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDE

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: HMGB1 (AAH03378.1, 1 a.a. ~ 215 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-HMGB1 Antikörper (ABIN1326935)

Kim, Ku, Bae: "Persicarin is anti-inflammatory mediator against HMGB1-induced inflammatory responses in HUVECs and in CLP-induced sepsis mice." in: Journal of cellular physiology, Vol. 228, Issue 4, pp. 696-703, (2013) (PubMed).

Lee, Ku, Kim, Bae: "Emodin-6-O-?-D-glucoside inhibits HMGB1-induced inflammatory responses in vitro and in vivo." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 52, pp. 97-104, (2013) (PubMed).

Details zu HMGB1

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Andere Bezeichnung: HMGB1

Hintergrund: Full Gene Name: high-mobility group box 1
Synonyms: DKFZp686A04236,HMG1,HMG3,SBP-1

Gen-ID: 3146

Pathways: p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome