LRRC4 Antikörper (AA 550-652)
Kurzübersicht für LRRC4 Antikörper (AA 550-652) (ABIN1304867)
Target
Alle LRRC4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 550-652
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Spezifität
- No off-targets reported for NGL-1 or NGL-3
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
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Description: Our Anti-NGL-2/LRRC4 mouse monoclonal primary antibody is produced in-house from hybridoma clone N50/36. It is KO validated, detects mouse and rat NGL-2/LRRC4, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Manufacturer Comment: We produce our NGL-2/LRRC4 mouse monoclonal primary antibody from hybridoma clone N50/36. It is great in IHC, ICC, WB and is purified by Protein A chromatography.
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Aufreinigung
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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Reinheit
- > 90% specific antibody
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Immunogen
- Fusion protein amino acids 550-652 of mouse NGL-2 (accession number AAG60620) produced recombinantly in E. Coli
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Isotyp
- IgG1
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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Haltbarkeit
- 24 months
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- LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
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Andere Bezeichnung
- LRRC4
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Hintergrund
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Synonyms: Leucine-rich repeat-containing protein 4 (Brain tumor-associated protein MBAG1) (Netrin-G2 ligand) (NGL-2)
Target Description: Leucine Rich Repeat Containing 4 is encoded by the gene LRRC4. LRRC4 is a synaptic adhesion protein that regulates the formation of excitatory synapses through the recruitment of pre and postsynaptic proteins. LRRC4 organizes the lamina pathway-specific differentiation of dendrites, and plays an important role in auditory synaptic responses. LRRC4 is expressed in the brain. LRRC4 is significantly downregulated in primary brain tumors.
Gene Name Alternatives: Lrrc4
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Molekulargewicht
- 100 kDa
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UniProt
- Q99PH1
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Pathways
- Synaptic Membrane
Target
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