MFN1 Antikörper (AA 350-580)
Kurzübersicht für MFN1 Antikörper (AA 350-580) (ABIN1304824)
Target
Alle MFN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 350-580
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Spezifität
- No off-targets reported for Mitofusin-2
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
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Description: Our Anti-Mitofusin-1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N111/24. It is KO validated, detects mouse and rat Mitofusin-1, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Manufacturer Comment: We produce our Mitofusin-1 mouse monoclonal primary antibody from hybridoma clone N111/24. It is great in ICC, WB and is purified by Protein A chromatography.
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Aufreinigung
- Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.
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Reinheit
- > 90% specific antibody
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Immunogen
- Fusion protein amino acids 350-580 of mouse Mitofusin-1 (accession number Q811U4) produced recombinantly in E. Coli
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Isotyp
- IgG1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
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Haltbarkeit
- 24 months
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- MFN1 (Mitofusin 1 (MFN1))
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Andere Bezeichnung
- Mitofusin-1
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Hintergrund
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Synonyms: Mitofusin-1 (EC 3.6.5.-) (Transmembrane GTPase MFN1)
Target Description: Mitofusin 1, or transmembrane GTPase Mfn1 (MFN1) is a mitochondrial membrane protein with GTPase activity that functions to aid mitochondrial clustering and fusion. It may also play a role in mitochondrial metabolism. It is expressed in the outer membrane of mitochondria in many tissues, including heart and testis. Diseases associated with MFN1 include Optic Atrophy 1 and Autosomal Recessive Spastic Paraplegia .
Gene Name Alternatives: Mfn1
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Molekulargewicht
- 80 kDa
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UniProt
- Q811U4
Target
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