MESDC2 Antikörper (AA 30-95)

Produktnummer ABIN1304817

Dieses Anti-MESDC2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MESDC2 in WB, IHC, ICC und IP. Geeignet für Maus.

Kurzübersicht für MESDC2 Antikörper (AA 30-95) (ABIN1304817)

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MESDC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Klon: N88-12

Produktdetails anti-MESDC2 Antikörper

Bindungsspezifität: AA 30-95

Spezifität: No off-targets reported

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-MESD mouse monoclonal primary antibody is produced in-house from hybridoma clone N88/12. It detects human, mouse, and rat MESD, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our MESD mouse monoclonal primary antibody from hybridoma clone N88/12. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Fusion protein amino acids 30-95 and 118-180 (lacking VSD domain) of mouse MESD (accession number Q9ERE7) produced recombinantly in E. Coli

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu MESDC2

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Andere Bezeichnung: MESD

Hintergrund:

Synonyms: LRP chaperone MESD (LDLR chaperone MESD) (Mesoderm development candidate 2) (Mesoderm development protein)

Target Description: Mesoderm Development LRP Chaperone is encoded by the gene MESD. MESD is a member of the MESD family. MESD is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). MESD acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. MESD is essential for the specification of embryonic polarity and mesoderm induction. MESD plays an essential role neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4. MESD is expressed in many tissues, but not in skeletal muscles. Diseases associated with MESD include Osteogenesis Imperfecta, Type Xx and Epilepsy, Nocturnal Frontal Lobe, 2.

Gene Name Alternatives: Mesd Mesdc2

Molekulargewicht: 26 kDa

UniProt: Q9ERE7