NHLRC1 Antikörper (AA 1-395)

Produktnummer ABIN1304811

Produktdetails anti-NHLRC1 Antikörper

Target: NHLRC1 (NHL Repeat Containing 1 (NHLRC1))

Bindungsspezifität: AA 1-395

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NHLRC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC)

Spezifität: No off-targets reported

Kreuzreaktivität: Human, Maus, Non-Human Primate, Ratte

Produktmerkmale:

Description: Our Anti-Malin mouse monoclonal primary antibody is produced in-house from hybridoma clone N85/18. It detects human, mouse, non-human primate, rat Malin, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Manufacturer Comment: We produce our Malin mouse monoclonal primary antibody from hybridoma clone N85/18. It is great in ICC, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Fusion protein amino acids 1-395 (full-length) of human malin (accession number AAQ19671) produced recombinantly in E. Coli

Klon: N85-18

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu NHLRC1

Target: NHLRC1 (NHL Repeat Containing 1 (NHLRC1))

Andere Bezeichnung: Malin (NHLRC1 Produkte)

Hintergrund:

Synonyms: E3 ubiquitin-protein ligase NHLRC1 (EC 2.3.2.27) (Malin) (NHL repeat-containing protein 1) (RING-type E3 ubiquitin transferase NHLRC1)

Target Description: NHL Repeat Containing E3 Ubiquitin Protein Ligase 1 is encoded by the gene NHLRC1. NHLRC1 is an E3 ubiquitin-protein ligase which is involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. NHLRC1 is expressed in the brain, spinal cord, heart, liver, skeletal muscle, and pancreas. Diseases associated with NHLRC1 include Myoclonic Epilepsy of Lafora and Epilepsy.

Gene Name Alternatives: NHLRC1 EPM2B

Molekulargewicht: 42 kDa