DREAM Antikörper (AA 1-256)

Produktnummer ABIN1304732

Der Maus Monoklonal Anti-DREAM-Antikörper wurde für WB, IHC, ICC und IP validiert. Er ist geeignet, DREAM in Proben von Ratte zu detektieren.

Kurzübersicht für DREAM Antikörper (AA 1-256) (ABIN1304732)

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DREAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Klon: K66-38

Produktdetails anti-DREAM Antikörper

Bindungsspezifität: AA 1-256

Spezifität: No off-targets reported for rat KChIPs 1,2, 4

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale:

Description: Our Anti-KChIP3 K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone K66/38. It is KO validated, detects human, mouse, and rat KChIP3 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Manufacturer Comment: We produce our KChIP3 K+ channel mouse monoclonal primary antibody from hybridoma clone K66/38. It is great in IHC, ICC, IP, WB and is purified by Protein A chromatography.

Aufreinigung: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography.

Reinheit: > 90% specific antibody

Immunogen: Fusion protein amino acids 1-256 (full length) of rat Calsenillin/DREAM/KChIP3 (accession number Q9JM47) produced recombinantly in E. Coli

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Dilution Range: IHC: 1:250

Dilution Range: ICC: 1:250

Dilution Range: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 10 mM Tris, 50 mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Haltbarkeit: 24 months

Details zu DREAM

Target: DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))

Andere Bezeichnung: KChIP3 K+ channel

Hintergrund:

Synonyms: Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3)

Target Description: Kchip3 potassium channel, also known as Kv channel-interacting protein 3, Kcnip3, DREantagonist modulator and Dream is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin or neuronal calcium sensor (NCS) family branch of the EF-hand superfamily. Kchip3 is an integral subunit component of native Kv4 channel complexes that may regulate A-type currents and function as a calcium regulated transcriptional repressor. Kchip3 is detected in brain, specifically in the cortex, thalamus, dentate gyrus and cerebellum and can be found throughout the cell. It is also found in other tissues at low levels. Diseases associated with KCNIP3 include alzheimer disease.

Gene Name Alternatives: Kcnip3 Csen Dream Kchip3

Molekulargewicht: 34 kDa

UniProt: Q9JM47