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FGFR4 Antikörper (Fibroblast Growth Factor Receptor 4) (PE) Primary Antibody

FGFR4 Reaktivität: Human ICC, FACS Wirt: Maus Monoclonal 4FR6D3 PE
Produktnummer ABIN1303110
$484.24
Zzgl. Versandkosten $45.00
100 tests
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 5 bis 7 Werktagen
  • Target Alle FGFR4 Antikörper anzeigen
    FGFR4
    Reaktivität
    • 93
    • 38
    • 25
    • 2
    • 1
    • 1
    Human
    Wirt
    • 79
    • 21
    Maus
    Klonalität
    • 75
    • 25
    Monoklonal
    Konjugat
    • 53
    • 8
    • 8
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FGFR4 Antikörper ist konjugiert mit PE
    Applikation
    • 63
    • 56
    • 30
    • 22
    • 16
    • 13
    • 13
    • 11
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody 4FR6D3 reacts with CD334, the fibroblast growth factor receptor 4, which is an approximately 88 kDa receptor tyrosine kinase expressed in variety of tissues.
    Kreuzreaktivität (Details)
    Human
    Immunogen
    NIH 3T3 cells transfected with full length human CD334
    Klon
    4FR6D3
    Isotyp
    IgG1
  • Applikationshinweise
    The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
  • Target
    FGFR4
    Andere Bezeichnung
    CD334 / FGFR4 (FGFR4 Produkte)
    Synonyme
    FGFR4, XFGFR-4, XFGFR-4a, cd334, fgfr-4, jtk2, tkf, xfgfr4, CD334, JTK2, TKF, Fgfr-4, etID309818.21, wu:fc13h10, zgc:111935, fgfr-4c, fgfr4, fibroblast growth factor receptor 4, fibroblast growth factor receptor 4 S homeolog, FGFR4, fgfr4, Fgfr4, fgfr4.S
    Hintergrund
    CD334 / FGFR4 (fibroblast growth factor receptor 4), a transmembrane tyrosine kinase, which is expressed in many tissues, such as in lung, kidney, muscle, heart, pancreas, intestine and other, acts as a receptor for several fibroblast growth factors, namely FGF1, FGF2, FGF6, FGF8, and FGF19. Interaction with these growth factors initiates in cell the signaling cascades leading to the mitogenesis and cell differentiation. Presence of CD334 Gly338Arg allele correlates with prognostic parameters in various cancer studies. CD334 plays multiple roles in the organism, including those of muscle regeneration, cholesterol-to-bile acid metabolism, or glucose homeostasis.
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
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