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FLT3 Antikörper (Fms-Related tyrosine Kinase 3) (APC) Primary Antibody

FLT3 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal BV10A4 APC
Produktnummer ABIN1302621
$484.24
Zzgl. Versandkosten $45.00
100 tests
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 5 bis 7 Werktagen
  • Target Alle FLT3 Antikörper anzeigen
    FLT3
    Reaktivität
    • 186
    • 62
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 187
    • 17
    • 2
    • 1
    Maus
    Klonalität
    • 188
    • 19
    Monoklonal
    Konjugat
    • 85
    • 15
    • 13
    • 11
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    Dieser FLT3 Antikörper ist konjugiert mit APC
    Applikation
    • 102
    • 95
    • 54
    • 54
    • 40
    • 29
    • 26
    • 15
    • 15
    • 14
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Spezifität
    The mouse monoclonal antibody BV10A4 (BV10) reacts with CD135 (FLT3, FLK2, STK-1), a 130-160 kDa type I transmembrane receptor tyrosine kinase that is involved in early steps of hematopoiesis.
    Keine Kreuzreaktivität
    Maus
    Kreuzreaktivität (Details)
    Human
    Immunogen
    BV-173 leukemic cell line
    Klon
    BV10A4
    Isotyp
    IgG1
  • Applikationshinweise
    The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
  • Target
    FLT3
    Andere Bezeichnung
    CD135 (FLT3 Produkte)
    Synonyme
    FLT3, B230315G04, CD135, Flk-2, Flk2, Flt-3, Ly72, wmfl, FLK-2, FLK2, STK1, fms related tyrosine kinase 3, FMS-like tyrosine kinase 3, fms-related tyrosine kinase 3, FLT3, Flt3
    Hintergrund
    CD135 / FLT3, also known as FLK2 or STK-1 is a receptor tyrosine kinase that plays important roles in hematopoiesis. After binding of Flt3 ligand (FL), CD135 homodimerizes and stimulates proliferation, differentiation and protects the cell from apoptosis. The loss of CD90 and gain of CD135 expression marks the loss of self-renewal in hematopoietic stem cell population. Detectable CD135 expression appears first at low levels on the surface of primitive multilineage progenitor cells and disappears during defined stages of B-cell development, but is upregulated and maintained during maturation of monocytes. CD135 is also expressed on thymocytes, dendritic cell progenitors and on mature dendritic cells, as well as on various malignant hematopoietic cells.
    Pathways
    RTK Signalweg
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