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beta Actin Antikörper (Actin, beta) AA 359-368 Primary Antibody

ACTB Reaktivität: Human IHC, ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (31 references)
Produktnummer ABIN129657
$547.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
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Lieferung in 1 bis 2 Werktagen
  • Target Alle beta Actin (ACTB) Antikörper anzeigen
    beta Actin (ACTB)
    Bindungsspezifität
    • 53
    • 18
    • 17
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 359-368
    Reaktivität
    • 241
    • 176
    • 160
    • 86
    • 77
    • 59
    • 52
    • 48
    • 41
    • 38
    • 27
    • 22
    • 18
    • 13
    • 12
    • 10
    • 8
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 136
    • 130
    • 6
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 144
    • 131
    Polyklonal
    Konjugat
    • 171
    • 20
    • 17
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser beta Actin Antikörper ist unkonjugiert
    Applikation
    • 232
    • 107
    • 87
    • 84
    • 48
    • 39
    • 34
    • 30
    • 13
    • 9
    • 7
    • 7
    • 7
    • 5
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Ratte (Rattus), Human, Affe, Schaf, Rind (Kuh), Ziege, Meerschweinchen, Schwein, Hamster
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    beta-Actin Loading Control Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 359-368 of Human beta Actin.
    Isotyp
    IgG
  • Applikationshinweise
    Anti-beta Actin Antibody has been tested for use in ELISA, immunohistochemistry and western blot. Specific conditions for reactivity should be optimized by the end user. Beta actin present in fibroblast connective tissue stains very brightly. Beta actin present in neuromuscular junctions also stains. Paraformaldehyde fixation yields brighter staining than formalin or methanol fixation. Expect a band at ~42 kDa in size corresponding to beta actin by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Olive, Qin, DeCristo, Laszewski, Greathouse, McAllister: "Accounting for tumor heterogeneity when using CRISPR-Cas9 for cancer progression and drug sensitivity studies." in: PLoS ONE, Vol. 13, Issue 6, pp. e0198790, (2019) (PubMed).

    Dai, Luftig: "Intracellular BH3 Profiling Reveals Shifts in Antiapoptotic Dependency in Human B Cell Maturation and Mitogen-Stimulated Proliferation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 5, pp. 1727-1736, (2019) (PubMed).

    Borroni, Emanuelli, Shah, Ilić, Apel-Sarid, Paolini, Manikoth Ayyathan, Koganti, Levy-Cohen, Blank: "Smurf2 regulates stability and the autophagic-lysosomal turnover of lamin A and its disease-associated form progerin." in: Aging cell, Vol. 17, Issue 2, (2018) (PubMed).

    Coleman, Ha, Haeryfar, Barr, Kim: "Cathepsin B plays a key role in optimal production of the influenza A virus." in: Journal of virology & antiviral research, Vol. 2018, pp. 1-20, (2018) (PubMed).

    Lodola, Laforenza, Cattaneo, Ruffinatti, Poletto, Massa, Tancredi, Zuccolo, Khdar, Riccardi, Biggiogera, Rosti, Guerra, Moccia: "VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells." in: Oncotarget, Vol. 8, Issue 56, pp. 95223-95246, (2017) (PubMed).

    Chen, Wang, Man, Li, Shan: "Increased B7-H4 expression during esophageal squamous cell carcinogenesis is associated with IL-6/STAT3 signaling pathway activation in mice." in: Oncology letters, Vol. 13, Issue 4, pp. 2207-2215, (2017) (PubMed).

    Rae, Hocum, Bii, Deeg, Trobridge: "A novel retroviral mutagenesis screen identifies prognostic genes in RUNX1 mediated myeloid leukemogenesis." in: Oncotarget, Vol. 6, Issue 31, pp. 30664-74, (2016) (PubMed).

    Koh, Powell, Blake, Hoffman, Hopkins, Feng: "Enhanced cytotoxicity in triple-negative and estrogen receptor‑positive breast adenocarcinoma cells due to inhibition of the transient receptor potential melastatin-2 channel." in: Oncology reports, Vol. 34, Issue 3, pp. 1589-98, (2016) (PubMed).

    Campos, Qiu, Gomero, Wakefield, Horner, Brutkowski, Han, Solecki, Frase, Bongiovanni, dAzzo: "Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier." in: Nature communications, Vol. 7, pp. 11876, (2016) (PubMed).

    Hopkins, Feng, Liu, Parker, Koh: "Inhibition of the transient receptor potential melastatin-2 channel causes increased DNA damage and decreased proliferation in breast adenocarcinoma cells." in: International journal of oncology, Vol. 46, Issue 5, pp. 2267-76, (2015) (PubMed).

    Maragkoudaki, Vaiopoulou, Theodoropoulos, Legaki, Sechi, Karamanolis, Zografos, Gazouli: "Specific detection of OCT4 isoforms in inflammatory bowel disease." in: Gut pathogens, Vol. 7, pp. 25, (2015) (PubMed).

    Zha, Xia, Ding, Choi, Yang, Dong, Yan, Huang, Ding: "MEIS2 is essential for neuroblastoma cell survival and proliferation by transcriptional control of M-phase progression." in: Cell death & disease, Vol. 5, pp. e1417, (2015) (PubMed).

    Nelson, Estus, Abner, Parikh, Malik, Neltner, Ighodaro, Wang, Wilfred, Wang, Kukull, Nandakumar, Farman, Poon, Corrada, Kawas, Cribbs, Bennett, Schneider, Larson, Crane, Valladares, Schmitt, Kryscio et al.: "ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. ..." in: Acta neuropathologica, Vol. 127, Issue 6, pp. 825-43, (2015) (PubMed).

    Wang, Choi, Ding, Yang, Ngoka, Lee, Zha, Mao, Jin, Ren, Cowell, Huang, Shi, Cui, Ding: "HOXC9 directly regulates distinct sets of genes to coordinate diverse cellular processes during neuronal differentiation." in: BMC genomics, Vol. 14, pp. 830, (2014) (PubMed).

    Dragoni, Laforenza, Bonetti, Reforgiato, Poletto, Lodola, Bottino, Guido, Rappa, Pareek, Tomasello, Guarrera, Cinelli, Aronica, Guerra, Barosi, Tanzi, Rosti, Moccia: "Enhanced expression of Stim, Orai, and TRPC transcripts and proteins in endothelial progenitor cells isolated from patients with primary myelofibrosis." in: PLoS ONE, Vol. 9, Issue 3, pp. e91099, (2014) (PubMed).

    Dragoni, Turin, Laforenza, Potenza, Bottino, Glasnov, Prestia, Ferulli, Saitta, Mosca, Guerra, Rosti, Luinetti, Ganini, Porta, Pedrazzoli, Tanzi, Montagna, Moccia: "Store-operated Ca2+ entry does not control proliferation in primary cultures of human metastatic renal cellular carcinoma." in: BioMed research international, Vol. 2014, pp. 739494, (2014) (PubMed).

    Wang, Danaher, Miller, Berger, Nubia, Wilfred, Neltner, Norris, Nelson: "Expression of miR-15/107 family microRNAs in human tissues and cultured rat brain cells." in: Genomics, proteomics & bioinformatics, Vol. 12, Issue 1, pp. 19-30, (2014) (PubMed).

    Papaconstantinou, Zeglinas, Gazouli, Nastos, Yiallourou, Lykoudis, Evangelou, Papalois, Papaioannou, Vlachogiannakos, Tzathas: "Effect of infliximab on the healing of intestinal anastomosis. An experimental study in rats." in: International journal of surgery (London, England), Vol. 12, Issue 9, pp. 969-75, (2014) (PubMed).

    Laforenza, Scaffino, Gastaldi: "Aquaporin-10 represents an alternative pathway for glycerol efflux from human adipocytes." in: PLoS ONE, Vol. 8, Issue 1, pp. e54474, (2013) (PubMed).

    Lodola, Laforenza, Bonetti, Lim, Dragoni, Bottino, Ong, Guerra, Ganini, Massa, Manzoni, Ambudkar, Genazzani, Rosti, Pedrazzoli, Tanzi, Moccia, Porta: "Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients." in: PLoS ONE, Vol. 7, Issue 9, pp. e42541, (2013) (PubMed).

  • Target
    beta Actin (ACTB)
    Andere Bezeichnung
    beta Actin (ACTB Produkte)
    Synonyme
    BRWS1, PS1TP5BP1, ACTA1, Actx, E430023M04Rik, beta-actin, ps1tp5bp1, act-2, actb, B-actin, LOC100174883, LOC100304816, A, ACT5C, Ac5C, Act, Act-5C, Act5, Act5c, Actin, Actin/BAP47, Actin5C, BAP47, Bap47, CG4027, Dmel\\CG4027, M32055, T11, act, act 5C, act5C, actin, actin5C, anon-EST:fe2D2, beta-actin/Bap47, cyt5C, l(1)G0009, l(1)G0010, l(1)G0025, l(1)G0079, l(1)G0117, l(1)G0177, l(1)G0245, l(1)G0330, l(1)G0420, l(1)G0486, Bact, ACT-5, ACTB, B-ACTZF, actba, bact, bactin1, bactzf, wu:fd18f05, A26C1B, POTE2alpha, POTEACTIN, Beta-actin, actin beta, actin, beta, cytoplasmic actin OlCA1, beta-actin, Actin 5C, actin gamma 1, actin, beta 1, actin, beta L homeolog, beta actin, POTE ankyrin domain family member F, actin, cytoplasmic 1, ACTB, Actb, actb, LOC100174883, LOC100304816, Act5C, ACTG1, actb1, actb.L, LOC100136352, POTEF, LOC109073280
    Hintergrund
    In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Beta and gamma actins coexist in most cell types as components of the cyto-skeleton and as mediators of internal cell motility. Beta actins are highly conserved proteins that are involved in cell motility, structure and integrity. Beta actins are cytoplasmic proteins. Anti-Actin is a loading control antibody and is critical for the correct interpretation of your western blot. Beta-Actin Loading Control Antibody is used to normalize the levels of protein detected by confirming that protein loading is uniform across the gel.
    Synonyms: Actin Antibody, Loading Control Antibody, beta actin, ß actin, anti-beta actin antibody
    Gen-ID
    4501885
    UniProt
    P60709
    Pathways
    Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction
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